PROGRAMME
Monday July 14th 2008
11:30 – 13:30 Registration, snacks
13.30 – 13:40 Welcome
13:40 - 17:55 Session: Entry and Host Interactions
Chairs: Dave Stuart, Felix Rey
13:40 – 14:15 Felix Rey
Crystal structure of the Rubella virus membrane fusion glycoprotein E1 in its post fusion conformation
14:15 – 14:50 Winfried Weissenhorn
Assembly of ESCRT-III and its role in enveloped virus budding
14:50 – 15:20 Eric Huizinga
Structures of corona- and torovirus hemagglutinin-esterases offer insight in receptor specificity and evolution
15:20 – 16:00 Coffee Break
16:00 – 16:35 Katsumi Maenaka
Crystal structure of measles virus hemagglutinin provides the molecular basis for effective vaccination
16:35– 17:10 Dieter Blaas
Structural Basis of Rhinovirus-Receptor Interaction and Early Processes in Infection
17:10– 17:40 Jan Kadlec
Crystal structure of the postfusion form of the baculovirus GP64 protein
17:40 – 18:00 Ulrike Maurer
Native 3D analysis of membrane fusion in Herpes simplex virus 1 entry: from a complex virus-host system to single players
Free evening
Tuesday July 15h 2008
9:00 - 12:00 Session: Entry and Host Interactions (cont)
Chairs: Winfried Weissenhorn
9:00 – 9:35 Jon Grimes
TBA
9:35– 10:00 Mark Van-Raaij
Structure of avian reovirus fibre Sigma-C and of its double-stranded RNA-binding protein Sigma-A
10:00– 10:25 Eike Schultz
Host Recognition of Bacteriohphage K1F: The product complex of EndoNF
10:25 – 11:00 Coffee Break
11:00 - 12:20 Session: Replication
Chairs: Bruno Canard
11:00 – 11:35 Stephen Cusack
Structure-function relationships of three domains of influenza virus polymerase subunit PB2
11:35 – 12:10 Hongmin Li
Structure and function of flavivirus NS5 methyltransferase
12:10 – 12:45 Martino Bolognesi
Recognition of RNA cap analogues by Wesselsbron virus NS5 methyl-transferase domain. Implications for flaviviral RNA capping mechanism
12:45 - 15:00 Lunch break and Poster session
15:00 – 15:55 Session: Replication (cont)
Chairs: Paul Tucker
15:00 – 15:35 Rolf Hilgenfeld
Proteases of RNA viruses and retroviruses: Structures, inhibitors, and resistance
15:35 – 16:10 Bruno Canard
The Structural Enzymologist's Gold Mine: The RNA Replication Machinery of Nidovirales
16:10 – 16:30 Mario Milani
Structural based inhibition of flavivirus replication enzymes: Helicase and Methyltransferase
16:30 – 17:00 Coffee Break
17:00 – 18:10 Session: Assembly and Future Perspectives
Chairs: Martino Bolognesi
17:00 – 17:35 Rob Ruigrok
Structure of negative strand RNA virus nucleocapsids
17:35 – 18:10 Stephen Graham
The structures of two rhabovirus matrix (m) proteins reveal a novel mode of self association
20:00 Workshop dinner Rathhaus keller
Wednesday July 16th 2008
9:30: 12:50 Session: Assembly and Future Perspectives
Chairs: Stephen Graham, Rolf Hilgenfeld
09:30 – 10:05 Dennis Bamford
Virion architecture and packaging system as probes for virus evolution and classification
10:05 – 11:40 Alisdair Steven
DNA Packaging and Capsid-based Signaling as Regulators of Virus Maturation
10:40 – 11:20 Coffee break
11:20 – 11:55 Herman van Tillbeurgh
VIRAR : a structural genomics project on archaeal virus proteins
11:55 – 12:30 Gerard Bricogne
Some recent developments in instrumentation, protocols and software aimed at challenging structure determination projects
12:30 – 12:40 Concluding remarks
12:40 – 14:00 Lunch