PROGRAMME

Monday July 14th 2008

 

11:30 – 13:30           Registration, snacks                        

 

13.30 – 13:40                          Welcome

 

 

13:40 - 17:55              Session: Entry and Host Interactions

                                      Chairs: Dave Stuart, Felix Rey

 

13:40 – 14:15                       Felix Rey      

Crystal structure of the Rubella virus membrane fusion glycoprotein E1 in its post fusion conformation

 

14:15 – 14:50                       Winfried Weissenhorn

Assembly of ESCRT-III and its role in enveloped virus budding

 

14:50 – 15:20                        Eric Huizinga

Structures of corona- and torovirus hemagglutinin-esterases offer insight in receptor specificity and evolution

 

15:20 – 16:00                       Coffee Break

 

16:00 – 16:35                       Katsumi Maenaka

                                               Crystal structure of measles virus hemagglutinin provides the molecular basis for effective vaccination

 

16:35– 17:10                        Dieter Blaas             

Structural Basis of Rhinovirus-Receptor Interaction and Early Processes in Infection

 

17:10– 17:40                         Jan Kadlec

Crystal structure of the postfusion form of the baculovirus GP64 protein

 

17:40 – 18:00                        Ulrike Maurer

Native 3D analysis of membrane fusion in Herpes simplex virus 1 entry: from a complex virus-host system to single players

 

 

Free evening

Tuesday July 15h 2008

 

9:00 - 12:00                Session: Entry and Host Interactions (cont)

                                      Chairs: Winfried Weissenhorn

 

9:00 – 9:35                            Jon Grimes

                                               TBA

 

 

9:35– 10:00                           Mark Van-Raaij

Structure of avian reovirus fibre Sigma-C and of its double-stranded RNA-binding protein Sigma-A

 

10:00– 10:25                         Eike Schultz

Host Recognition of Bacteriohphage K1F: The product complex of EndoNF

 

10:25 – 11:00                       Coffee Break

 

11:00 - 12:20              Session: Replication

                                      Chairs: Bruno Canard

 

11:00 – 11:35                        Stephen Cusack

Structure-function relationships of three domains of influenza virus polymerase subunit PB2

 

11:35 – 12:10                        Hongmin Li

                                               Structure and function of flavivirus NS5 methyltransferase

 

12:10 – 12:45                       Martino Bolognesi

                                                Recognition of RNA cap analogues by Wesselsbron virus NS5 methyl-transferase domain. Implications for flaviviral RNA capping mechanism

 

12:45 - 15:00                         Lunch break and Poster session

 

15:00 – 15:55             Session: Replication (cont)

                          Chairs: Paul Tucker

 

15:00 – 15:35                       Rolf Hilgenfeld

                                                Proteases of RNA viruses and retroviruses: Structures, inhibitors, and resistance

 

15:35 – 16:10                        Bruno Canard                    

The Structural Enzymologist's Gold Mine: The RNA Replication Machinery of Nidovirales

 

16:10 – 16:30                       Mario Milani

                                               Structural based inhibition of flavivirus replication enzymes: Helicase and Methyltransferase

 

16:30 – 17:00                       Coffee Break

 


17:00 – 18:10             Session: Assembly and Future Perspectives

                                      Chairs: Martino Bolognesi

 

17:00 – 17:35                        Rob Ruigrok

                                               Structure of negative strand RNA virus nucleocapsids

 

17:35 – 18:10                       Stephen Graham

                                               The structures of two rhabovirus matrix (m) proteins reveal a novel mode of self association

 

 

20:00                                      Workshop dinner Rathhaus keller


 

Wednesday July 16th 2008

 

9:30: 12:50                 Session: Assembly and Future Perspectives

                                      Chairs: Stephen Graham, Rolf Hilgenfeld

 

09:30 – 10:05                        Dennis Bamford

Virion architecture and packaging system as probes for virus evolution and classification

 

10:05 – 11:40                       Alisdair Steven

DNA Packaging and Capsid-based Signaling as Regulators of Virus Maturation

 

10:40 – 11:20                        Coffee break

 

11:20 – 11:55                       Herman van Tillbeurgh

VIRAR : a structural genomics project on archaeal virus proteins

 

11:55 – 12:30                       Gerard Bricogne    

Some recent developments in instrumentation, protocols and software aimed at challenging structure determination projects

 

12:30 – 12:40                        Concluding remarks

 

12:40 – 14:00                        Lunch

 

 

 

 


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